During delayed cord clamping, breathing assistance with CPAP of 5 cm H20 and a FiO2 1.0 will be provided. If an infant is randomized to the DCC and High Oxygen concentration (DCC HI group), the following procedure will ensue:ĭuring delayed cord clamping, the infant will be gently stimulated by drying the infant with a sterile towel and provide CPAP by 30 seconds of life. During delayed cord clamping, breathing assistance with CPAP of 5 cm H20 and a FiO2 0.3 will be provided. If an infant is randomized to the DCC and Low Oxygen concentration (DCC LO group), the following procedure will ensue:ĭuring delayed cord clamping, the infant will be gently stimulated by drying the infant with a sterile towel and provide CPAP by 30 seconds of life. These beds are equipped with an oxygen blender, humidifier, t-piece resuscitator with mask, necessary to provide CPAP/PPV. The oxygen blender will be concealed from the clinical care team to ensure resuscitation maneuvers will not be biased.ĭata will be submitted to the statistician, who will remain blinded to the intervention for the duration of the study.Īt delivery, the infant will be placed on a platform that allows the infant to be close to the mother and the umbilical cord to remain intact for DCC. The research team member will not be involved in the clinical care of the infant.
The research team member will set the oxygen blender as indicated by the randomization card and cover the blender to blind the FiO2 setting. The research team member will open a randomization card when notified of a subject's impending birth, review the protocol with the obstetric provider performing the procedure, set-up the sterile stabilization bed, and note the time it takes from delivery until the clamping and cutting of the umbilical cord in both groups. Randomization and intervention will remain blinded to the clinical care team during the entire study period. 30) OR High oxygen concentration (FiO2 1.0) during 90 seconds of delayed cord clamping. Shortly before delivery, infant's will be randomly assigned to receive either Low oxygen concentration (FiO2. Prenatal consent will be obtained on infant's with estimated gestational age up to 28+6 weeks. Why Should I Register and Submit Results?.
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